Splice

2010 · directed by Vincenzo Natali

Rating

63/100

Hit

no

Elsa and Clive, two rebellious young scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators — only to have that bond turn deadly.

Splice (2010), directed by Vincenzo Natali, rates 63/100. See how its director, cast and crew rate across their careers.

Cast

• Adrien Brody
• Sarah Polley
• Delphine Chanéac
• Brandon McGibbon
• Simona Măicănescu
• David Hewlett
• Abigail Chu
• Doug Hicton

Crew

• Tetsuo Nagata — Director of Photography
• Michele Conroy — Editor
• Cyrille Aufort — Original Music Composer
• Antoinette Terry Bryant — Screenplay
• Doug Taylor — Screenplay
• Vincenzo Natali — Screenplay

More from Vincenzo Natali

1. Paris Je T'aime (2006) — 72/100
2. Cube (1998) — 66/100
3. Cypher (2002) — 64/100
4. ABCs of Death 2 (2014) — 57/100
5. Haunter (2013) — 56/100
6. Nothing (2003) — 52/100

How these numbers work: Methodology